Perry’s death was confirmed by Capt. Scot Williams of the Los Angeles Police Department’s robbery-homicide division, The New York Times reported.
The Los Angeles Times, citing anonymous sources, said that authorities responded to Perry’s home in the Pacific Palisades neighborhood of Los Angeles at about 4 p.m. PDT, where he was found unresponsive in a hot tub.
TMZ was the first outlet to report the actor’s death.
“Friends” star Mathew Perry was found dead Saturday in a hot tub at his Los Angeles home, law enforcement sources said. Authorities responded about 4 p.m. to his home, where he was discovered unresponsive.https://t.co/vfxvkix9y2pic.twitter.com/AAun9Y6wUi
TMZ, citing “law enforcement sources,” said that Perry was allegedly found in a jacuzzi; no drugs were found at the scene.
A 911 call came in at 4:07 p.m. PDT and was treated as a water rescue, a law enforcement source told NBC News.
Los Angeles Fire Department spokesperson Brian Humphrey said that no one was taken to a hospital, according to the news outlet.
Law enforcement sources did not provide a cause of death because the investigation was ongoing, the Los Angeles Times reported. There was no sign of foul play.
The Los Angeles Police Department’s robbery-homicide detectives are investigating the death, according to the newspaper.
Representatives for Perry did not immediately respond to People’s request for comment.
“We are devastated to learn of Matthew Perry’s passing,” Warner Bros. tweeted Saturday. “He was a true gift to us all. Our heart goes out to his family, loved ones, and all of his fans.”
We are devastated to learn of Matthew Perry’s passing. He was a true gift to us all. Our heart goes out to his family, loved ones, and all of his fans. pic.twitter.com/sAGMLmu5ki
Perry received a Primetime Emmy nomination in 2002 for his performance in “Friends,” Variety reported.
In his 2022 memoir, “Friends, Lovers and the Big Terrible Thing,” Perry wrote how longtime opioid use caused his colon to burst in 2018. He also touched on his lifelong struggle with opioids and alcohol, which led to several trips to rehabilitation centers, the Los Angeles Times reported.
“My friends call me Matty,” the book’s opening line reads, according to the newspaper. “And I should be dead.”
Perry first went to rehab in 1997 for what was described as an addiction to pain medication, The New York Times reported. In 2000, he was hospitalized for pancreatitis, according to the newspaper.
His addiction led to a series of complications in 2018. In addition to the burst colon, Perry suffered from pneumonia, was briefly on life support and spent two weeks in a coma, The New York Times reported. He also had more than a dozen stomach surgeries, according to the newspaper.
Born in Williamstown, Massachusetts, on Aug. 19, 1969, Matthew Langford Perry was raised in Ottawa, Canada, People reported. One of his classmates was future Canadian Prime Minister Justin Trudeau.
His mother, Suzanne Morrison, was a journalist and press secretary to Trudeau’s father, another Canadian prime minister -- Pierre Trudeau.
"'Friends' wouldn’t have been 'Friends' without Matthew Perry.
And neither would have been, as time went by, American culture. The actor, who infused the hit show with its vital, sustaining dose of sarcasm, went on in recent years to publicize his sobriety, and his work… pic.twitter.com/JXQniEmEIC
Perry’s stepfather is “Dateline’s” Keith Morrison, according to People. His father, John Bennett Perry, was an actor and model. Matthew Perry appeared in a 1979 episode of his father’s series, “240 Robert,” according to the magazine.
Shortly after 7 p.m. PDT, Perry’s mother and stepfather appeared at the actor’s home, The New York Times reported. They declined to comment, according to the newspaper.
Some of Matthew Perry’s funniest moments on ‘FRIENDS’ have been put together to honor him after his tragic passing. pic.twitter.com/NsJCybIjXE
Perry began his career as a child actor, guest starring on “Charles in Charge” and “Beverly Hills 90210,” the Los Angeles Times reported. He also played opposite River Phoenix in “A Night in the Life of Jimmy Reardon,” according to the newspaper.
But his big break came on “Friends,” where he starred with Jennifer Aniston, Courteney Cox, Lisa Kudrow, Matt LeBlanc and David Schwimmer.
In addition to “Friends,” Perry appeared in several comedy films, including “Fools Rush In,” “17 Again” and “The Whole Nine Yards,” KTLA-TV reported. He also appeared in “The West Wing” and “Scrubs,” NBC News reported.
He was the co-creator, executive producer and star of the sitcom “Mr. Sunshine,” which ran from February to April 2011, according to Variety.
Perry said he was on an “emotional roller coaster” because of the success of “Friends,” according to The Hollywood Reporter.
“There was steam coming out of my ears, I wanted to be famous so badly,” Perry said in a 2002 interview with The New York Times. “You want the attention, you want the bucks, and you want the best seat in the restaurant. I didn’t think what the repercussions would be. When (stardom) happens, it’s kind of like Disneyland for a while. For me, it lasted about eight months, this feeling of, ‘I’ve made it, I’m thrilled, there’s no problem in the world.’
A great video showing the evolution of Matthew Perry over the years. Rest in Peace. Chandler character in friends was one of the most iconic characters in TV. pic.twitter.com/JHcLmQhIoE
“And then you realize that it doesn’t accomplish anything, it’s certainly not filling any holes in your life.”
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Photos: Matthew Perry through the years 1994: Matthew Perry as Chandler Bing on "Friends" in 1994. (Reisig & Taylor/NBCU Photo Bank/NBCUniversal via Getty Images)
Photos: Matthew Perry through the years 1995: Matt LeBlanc, Jennifer Aniston, Matthew Perry, Lisa Kudrow, Courtney Cox and David Schwimmer of the TV show "Friends" attend the 21st annual People's Choice Awards on March 5, 1995, at the Universal Studios in Universal City, California. (Ron Davis/Getty Images)
Photos: Matthew Perry through the years 1997: "Friends" co-stars actress Lisa Kudrow and actor Matthew Perry attend the 49th annual Primetime Emmy Awards on September 14, 1997, at the Pasadena Civic Auditorium in Pasadena, California. (Ron Davis/Getty Images)
Photos: Matthew Perry through the years 1999: Actress Jennifer Aniston, actress Courteney Cox, actor Matt LeBlanc, actress Lisa Kudrow, actor Matthew Perry and actor David Schwimmer attend the fifth annual Screen Actors Guild Awards on March 7, 1999, at the Shrine Auditorium in Los Angeles. (Ron Galella, Ltd./Ron Galella Collection via Getty Images)
Photos: Matthew Perry through the years 2001: Left, Matthew Perry, Matt LeBlanc and David Schwimmer arrive at the 28th annual People's Choice Awards held at the Pasadena Civic Auditorium in Los Angeles on Jan. 13, 2001. (Kevin Winter/Getty Images)
Photos: Matthew Perry through the years 2002: Actors David Schwimmer, Lisa Kudrow, Matthew Perry, Courteney Cox Arquette, Jennifer Aniston and Matt LeBlanc pose backstage during the 54th annual Primetime Emmy Awards at the Shrine Auditorium on September 22, 2002, in Los Angeles. Aniston won Outstanding Lead Actress in a Comedy Series for "Friends." (Robert Mora/Getty Images)
Photos: Matthew Perry through the years 2003: Actor Matt LeBlanc, actress Lisa Kudrow and actor Matthew Perry pose during the ninth annual Screen Actors Guild Awards at the Shrine Auditorium on March 9, 2003, in Los Angeles. (Kevin Winter/Getty Images)
Photos: Matthew Perry through the years 2004: Actors Bruce Willis (left) and Matthew Perry talk at the after-party for the premiere of Warner Bros. "The Whole Ten Yards" at the Sunset Room on April 7, 2004, in Los Angeles. (Kevin Winter/Getty Images)
Photos: Matthew Perry through the years 2005: Actor Matthew Perry (left) and actress Courteney Cox arrive at the series premiere for TBS' "Daisy Does America" at Guy's on November 29, 2005, in Los Angeles. (Michael Buckner/Getty Images)
Photos: Matthew Perry through the years 2006: Actor Matthew Perry and actress Courteney Cox Arquette mingle at the AFI Associates luncheon honoring Hollywood's Arquette family with the 6th annual "Platinum Circle Award" held at the Regent Beverly Wilshire Hotel on May 10, 2006, in Beverly Hills, California. (Kevin Winter/Getty Images for AFI)
Photos: Matthew Perry through the years 2007: Actors Lisa Kudrow and Matthew Perry picket in support of the Writers Guild of America which is currently on-strike for increased residuals from film and television profits in front of the Universal Studios Lot November 13, 2007, in Universal City, California. (Matthew Simmons/Getty Images)
Photos: Matthew Perry through the years 2008: Actor Matthew Perry leaves the Dolce's Five Year Anniversary at the Dolce Enoteca on May 20, 2008, in Los Angeles. (Valerie Macon/Getty Images)
Photos: Matthew Perry through the years 2009: Actors Michelle Trachtenberg, Zac Efron, Leslie Mann and Matthew Perry arrive at the premiere of Warner Bros. "17 Again" held at Grauman's Chinese Theatre on April 14, 2009, in Hollywood, California. (Kevin Winter/Getty Images)
Photos: Matthew Perry through the years 2010: Actors Matthew Perry (left) and Lauren Graham present the Guest Actress & Actor in a Comedy Series awards onstage at the 62nd annual Primetime Emmy Awards held at the Nokia Theatre L.A. Live on August 29, 2010, in Los Angeles. (Kevin Winter/Getty Images)
Photos: Matthew Perry through the years 2011: Actor Matthew Perry and co-founder/editor-in-chief of The Huffington Post Arianna Huffington arrives at the Arianna Huffington & The Huffington Post presents Bill Maher and The Best of Huffpost Comedy event at The Roxy Theater on February 23, 2011, in West Hollywood, California. (Angela Weiss/Getty Images)
Photos: Matthew Perry through the years 2012: Actress Matthew Perry arrives at the 64th annual Primetime Emmy Awards at Nokia Theatre L.A. Live on September 23, 2012, in Los Angeles. (Frazer Harrison/Getty Images)
Photos: Matthew Perry through the years 2013: Actor Mathew Perry poses after the 2013 Huading Awards Ceremony at The Venetian on October 7, 2013, in Macau, Macau. (Lam Yik Fei/Getty Images for Global Talents Media Group)
Photos: Matthew Perry through the years 2014: Actors Matthew Perry (left) and Thomas Lennon attend the CBS, The CW, Showtime & CBS Television Distribution's 2014 TCA Summer Press Tour Party at Pacific Design Center on July 17, 2014, in West Hollywood, California. (Imeh Akpanudosen/Getty Images)
Photos: Matthew Perry through the years 2015: Actor Matthew Perry attends Venice Family Clinic's Silver Circle Gala at Regent Beverly Wilshire Hotel on March 9, 2015, in Beverly Hills, California. (Mike Windle/Getty Images for Venice Family Clinic)
Photos: Matthew Perry through the years 2016: Actors Thomas Lennon (left), Wendell Pierce, Yvette Nicole Brown, Lindsay Sloane and Matthew Perry attend the CBS, CW, Showtime Summer TCA Party at Pacific Design Center on August 10, 2016, in West Hollywood, California. (Matt Winkelmeyer/Getty Images)
Photos: Matthew Perry through the years 2017: Actors Katie Holmes (left) and Matthew Perry at the premiere of Reelz's "The Kennedys After Camelot" at The Paley Center for Media on March 15, 2017, in Beverly Hills, California. (Frazer Harrison/Getty Images)
Photos: Matthew Perry through the years 2022: Matthew Perry looks on during the Women’s Singles Final match between Iga Swiatek of Poland and Ons Jabeur of Tunisia on Day Thirteen of the 2022 US Open at USTA Billie Jean King National Tennis Center on September 10, 2022, in the Flushing neighborhood of the Queens borough of New York City. (Elsa/Getty Images)
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Remembering Matthew Perry A person takes pictures of a makeshift memorial for Matthew Perry outside the building known as the "Friends" building in New York, Sunday, Oct. 29, 2023. Fans lingered in the rain, taking pictures and leaving flowers on the corner outside the building shown in exterior shots on the popular TV show. Perry, who played Chandler Bing on NBC’s “Friends” for 10 seasons, was found dead at his Los Angeles home on Saturday. He was 54. (AP Photo/Brooke Lansdale) (Brooke Lansdale/AP)
Remembering Matthew Perry A makeshift memorial for Matthew Perry is seen outside the building known as the "Friends" building in New York, Sunday, Oct. 29, 2023. Fans lingered in the rain, taking pictures and leaving flowers on the corner outside the building shown in exterior shots on the popular TV show. Perry, who played Chandler Bing on NBC’s “Friends” for 10 seasons, was found dead at his Los Angeles home on Saturday. He was 54. (AP Photo/Brooke Lansdale) (Brooke Lansdale/AP)
Remembering Matthew Perry A makeshift memorial for Matthew Perry is seen outside the building known as the "Friends" building in New York, Sunday, Oct. 29, 2023. Fans lingered in the rain, taking pictures and leaving flowers on the corner outside the building shown in exterior shots on the popular TV show. Perry, who played Chandler Bing on NBC’s “Friends” for 10 seasons, was found dead at his Los Angeles home on Saturday. He was 54. (AP Photo/Brooke Lansdale) (Brooke Lansdale/AP)
Remembering Matthew Perry Fans place flowers at a makeshift memorial for Matthew Perry outside the building known as the "Friends" building in New York, Sunday, Oct. 29, 2023. People lingered in the rain, taking pictures and leaving flowers on the corner outside the building shown in exterior shots on the popular TV show. Perry, who played Chandler Bing on NBC’s “Friends” for 10 seasons, was found dead at his Los Angeles home on Saturday. He was 54. (AP Photo/Brooke Lansdale) (Brooke Lansdale/AP)
Remembering Matthew Perry People lay flower tributes to actor Matthew Perry outside the apartment building which was used as the exterior shot in the TV show "Friends" in New York on October 29, 2023. Perry, 54, was known globally for his portrayal of wise-cracking character Chandler Bing on the wildly popular "Friends," which ran for 10 seasons from 1994 to 2004. First responders found Perry unconscious in a hot tub at his house on October 28 and were unable to revive him, law enforcement sources told the Los Angeles Times. Police confirmed they'd mounted a "death investigation for a male in his 50s." (Photo by Adam GRAY / AFP) (Photo by ADAM GRAY/AFP via Getty Images) (ADAM GRAY/AFP via Getty Images)
Remembering Matthew Perry People place flowers in tribute to actor Matthew Perry outside the apartment building which was used as the exterior shot in the TV show "Friends" in New York on October 29, 2023. Perry, 54, was known globally for his portrayal of wise-cracking character Chandler Bing on the wildly popular "Friends," which ran for 10 seasons from 1994 to 2004. First responders found Perry unconscious in a hot tub at his house on October 28 and were unable to revive him, law enforcement sources told the Los Angeles Times. Police confirmed they'd mounted a "death investigation for a male in his 50s." (Photo by Adam GRAY / AFP) (Photo by ADAM GRAY/AFP via Getty Images) (ADAM GRAY/AFP via Getty Images)
Remembering Matthew Perry Floral tributes are left for actor Matthew Perry outside the apartment building which was used as the exterior shot in the TV show "Friends" in New York on October 29, 2023. Perry, 54, was known globally for his portrayal of wise-cracking character Chandler Bing on the wildly popular "Friends," which ran for 10 seasons from 1994 to 2004. First responders found Perry unconscious in a hot tub at his house on October 28 and were unable to revive him, law enforcement sources told the Los Angeles Times. Police confirmed they'd mounted a "death investigation for a male in his 50s." (Photo by Adam GRAY / AFP) (Photo by ADAM GRAY/AFP via Getty Images) (ADAM GRAY/AFP via Getty Images)
Remembering Matthew Perry Floral tributes are left for actor Matthew Perry outside the apartment building which was used as the exterior shot in the TV show "Friends" in New York on October 29, 2023. Perry, 54, was known globally for his portrayal of wise-cracking character Chandler Bing on the wildly popular "Friends," which ran for 10 seasons from 1994 to 2004. First responders found Perry unconscious in a hot tub at his house on October 28 and were unable to revive him, law enforcement sources told the Los Angeles Times. Police confirmed they'd mounted a "death investigation for a male in his 50s." (Photo by Adam GRAY / AFP) (Photo by ADAM GRAY/AFP via Getty Images) (ADAM GRAY/AFP via Getty Images)
Remembering Matthew Perry TOPSHOT - People stand in line to pay tribute to actor Matthew Perry outside the apartment building which was used as the exterior shot in the TV show "Friends" in New York on October 29, 2023. Perry, 54, was known globally for his portrayal of wise-cracking character Chandler Bing on the wildly popular "Friends," which ran for 10 seasons from 1994 to 2004. First responders found Perry unconscious in a hot tub at his house on October 28 and were unable to revive him, law enforcement sources told the Los Angeles Times. Police confirmed they'd mounted a "death investigation for a male in his 50s." (Photo by Adam GRAY / AFP) (Photo by ADAM GRAY/AFP via Getty Images) (ADAM GRAY/AFP via Getty Images)